I figured it was time for another "practical" post, so here is something I tried recently.
The other day, I noticed that our bathroom drain was looking a bit icky - I clean the sink and surrounding area at least once weekly, sometimes more - but drains totally gross me out. So, I was thinking of ways to try and avoid any kind of "hands on" cleaning approach to this.
Of course, my two favorite household staples came to mind - baking soda and vinegar. :) I grabbed the box of baking soda and my 1/2 gallon of vinegar and scampered back to the bathroom and proceeded to generously dump baking soda on and around the drain area. I added vinegar and witnessed that beautiful bubbling reaction. I repeated several times until the gunk right inside the drain was no longer noticeable.
All things considered, this worked beautifully. Sure, it may not be a super-thorough job, but I now deem the nastiness at least somewhat sanitized and minimized. And, best of all, I didn't have to touch any of it. :)